Transcriptional Profiling at High Temporal Resolution Reveals Robust Immune/Inflammatory Responses during Rat Sciatic Nerve Recovery

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td class="align_left">Molecules verified</td><td class="align_center">Pathways</td><td class="align_center">Function</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td class="align_left">SELP, SELE, SELPLG, SELL, ITGA4</td><td class="align_center">Agranulocyte/granulocyte adhesion and diapedesis</td><td class="align_center" rowspan="2">Extravasation of agranulocyte/granulocyte, including (1) tethering, (2) rolling and activation, (3) firm adhesion to the endothelium, (4) diapedesis, and (5) transendothelial migration</td></tr><tr><td class="align_left">ITGB7</td><td class="align_center">Agranulocyte adhesion and diapedesis</td></tr><tr><td class="align_left">JAK2</td><td class="align_center">IL-6</td><td class="align_center">Proinflammatory response</td></tr><tr><td class="align_left">IL-10</td><td class="align_center">IL-10</td><td class="align_center">Anti-inflammatory response</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Molecules verified and pathways involved.

Mediators of Inflammation

tab2

Table 2

Table 2: Transcriptional Profiling at High Temporal Resolution Reveals Robust Immune/Inflammatory Responses during Rat Sciatic Nerve Recovery 