Research Article

Cynanchum wilfordii Polysaccharides Suppress Dextran Sulfate Sodium-Induced Acute Colitis in Mice and the Production of Inflammatory Mediators from Macrophages

Table 2

Criteria for assessment of microscopic rectal damage.

ScoreObservation

0Normal colonic mucosa
1Loss of one-third of the crypts
2Loss of two-thirds of the crypts
3Lamina propria covered with a single layer of epithelial cells, with mild inflammatory cell infiltration
4Erosions and marked inflammatory cell infiltration

Mucosal damage was scored 0–4 based on the loss of crypts (mucosa) and infiltration of inflammatory cells (maximum score = 4).