Antitumor Macrophage Response to Bacillus pumilus Ribonuclease (Binase)

Figure 6

Binase-induced release of proinflammatory mediators in human THP-1-derived macrophages. THP-1-derived macrophages were treated in the absence (control) or presence of RNA (10 μg/ml), RNase1 (10 μg/ml), or binase (10 μg/ml) during 0.5 h, followed by a supernatant proteome/cytokine profiler array (R&D Systems). Values represent mean ± SD of the mean from three independent experiments performed in triplicates. versus control, ns = nonsignificant.