Clinical Study
Evaluation of Inflammatory Markers in a Large Sample of Obstructive Sleep Apnea Patients without Comorbidities
Table 2
Percentage of subjects with high inflammatory biomarkers in the four OSA severity groups.
| Variables | Controls | Mild | Moderate | Severe | value | value | value | value | value | value | value | Across all | Controls versus mild | Controls versus moderate | Controls versus severe | Mild versus moderate | Mild versus severe | Moderate versus severe |
| Hs-CRP (≥1 mg/dL) | 23% | 17.2% | 27.7% | 28.2% | 0.04 | 0.2 | 0.36 | 0.26 | 0.02 | 0.008 | 0.9 | Fibrinogen (>400 mg/dL) | 11.8% | 13.4% | 10.1% | 19.8% | 0.04 | 0.7 | 0.68 | 0.07 | 0.39 | 0.11 | 0.016 | ESR (>30 mm/hr) | 7.8% | 7.5% | 11.1% | 11.7% | 0.36 | 0.91 | 0.33 | 0.21 | 0.25 | 0.14 | 0.84 | UA (>7 mg/dL) | 6.8% | 8.6% | 13.7% | 17.5% | 0.003 | 0.51 | 0.036 | 0.001 | 0.14 | 0.008 | 0.32 |
|
|
hs-CRP: hs-C-reactive protein; ESR: erythrocyte sedimentation rate; UA: uric acid.
|