Clinical Study

Evaluation of Inflammatory Markers in a Large Sample of Obstructive Sleep Apnea Patients without Comorbidities

Table 2

Percentage of subjects with high inflammatory biomarkers in the four OSA severity groups.

VariablesControlsMildModerateSevere value value value value value value value
Across allControls versus mildControls versus moderateControls versus severeMild versus moderateMild versus severeModerate versus severe

Hs-CRP (≥1 mg/dL)23%17.2%27.7%28.2%0.040.20.360.260.020.0080.9
Fibrinogen (>400 mg/dL)11.8%13.4%10.1%19.8%0.040.70.680.070.390.110.016
ESR (>30 mm/hr)7.8%7.5%11.1%11.7%0.360.910.330.210.250.140.84
UA (>7 mg/dL)6.8%8.6%13.7%17.5%0.0030.510.0360.0010.140.0080.32

hs-CRP: hs-C-reactive protein; ESR: erythrocyte sedimentation rate; UA: uric acid.