Role of Cathepsin S in Periodontal Inflammation and Infection

Figure 1

(a) Effects of IL-1β (1 ng/mL) or F. nucleatum (OD: 0.025) on CTSS mRNA expression at 1 d. Untreated cells served as the control. Mean ± SEM (); significant () difference between groups. (b) Effects of various concentrations of F. nucleatum (OD: 0.00–0.05) on CTSS mRNA expression at 1 d and 2 d. Mean ± SEM (); significant () difference between groups. (c) Effects of IL-1β (1 ng/mL) or F. nucleatum (OD: 0.025) on CTSS mRNA expression in cells either preincubated or not with a specific MEK1/2 inhibitor (U0126) at 1 d. Untreated cells served as the control. Mean ± SEM (); significant () difference between groups.

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