Research Article

The Metabolic Syndrome, Inflammation, and Colorectal Cancer Risk: An Evaluation of Large Panels of Plasma Protein Markers Using Repeated, Prediagnostic Samples

Table 2

List of proteins significantly associated with MetS score or one of its components.

Protein nameUniProt numberAssociated withDirection of associationOriginal Olink panel

IL-6P05231BMIPositiveInflammation panel and oncology panel
TNFSF10P50591BMIPositiveInflammation panel and oncology panel
SEZ6LQ9BYH1BMINegativeOncology panel
FGF-BP1Q14512BMINegativeOncology panel
ESM-1Q9NQ30BMINegativeOncology panel
FGF-21Q9NSA1MetS and BMIPositiveInflammation panel
TNFSF14O43557MetS and BMIPositiveInflammation panel
HGFP14210MetS and BMIPositiveInflammation panel and oncology panel
FurinP09958MetS, BMI, and triglyceridesPositiveOncology panel
ERBB2P04626MetS and triglyceridesPositiveOncology panel
SCFP21583MetS and triglyceridesNegativeInflammation panel and oncology panel
OPGO00300Total cholesterolPositiveInflammation panel