Regulation of Ghrelin Receptor by Periodontal Bacteria In Vitro and In Vivo

Figure 2

(a) Stimulation of NF-κB (p65) nuclear translocation by F. nucleatum (OD₆₆₀: 0.1) in PDL cells over 60 min, as analyzed by immunofluorescence microscopy. Representative images from one out of three experiments are shown. (b) Expression of GHS-R1a in PDL cells stimulated with F. nucleatum (Fn; OD₆₆₀: 0.1) in the presence and absence of anti-TLR4 blocking antibody at 1 d, as determined by real-time PCR. Mean ± SEM (). Significant () difference between groups.

(a)

(b)