Regulation of Ghrelin Receptor by Periodontal Bacteria In Vitro and In Vivo

Figure 3

Expressions of CCL2 (a), IL-6 (b), and IL-8 (c) in PDL cells in the presence of F. nucleatum (Fn; OD₆₆₀: 0.1) and/or GHRL (20 nM) at 1 d, as analyzed by real-time PCR. Unstimulated cells served as control. Mean ± SEM (). Significant () difference between groups. (d) Expression of GHS-R1a in PDL cells in the presence and absence of GHRL (20 nM) at 1 d. Mean ± SEM (). Significant () difference between groups.

(a)

(b)

(c)

(d)