Pretreatment with Fish Oil-Based Lipid Emulsion Modulates Muscle Leukocyte Chemotaxis in Murine Model of Sublethal Lower Limb Ischemia

Table 2

Plasma concentrations of the cytokines.

	Sham	S0	F0	S24	F24
MCP-1 (pg/mL)	ND	5.04 ± 2.24	4.41 ± 2.07	16.4 ± 1.57	7.69 ± 2.32
MIP-2 (pg/mL)	0.38 ± 0.17	11.29 ± 4.29	7.03 ± 2.85	0.17 ± 0.11	0.66 ± 0.31
IL-6 (pg/mL)	1.15 ± 0.57	6.35 ± 2.61	7.16 ± 2.63	39.5 ± 3.74	23.37 ± 3.70

ND: not detectable. Sham group, without IR procedure; S0 group, ischemic mice pretreated with saline injection sacrificed immediately after onset of reperfusion (time 0); F0 group, ischemic mice pretreated with FO emulsion sacrificed at time 0; S24, ischemic mice pretreated with saline injection sacrificed at 24 h after reperfusion (time 24 h); F24, ischemic mice pretreated with FO emulsion sacrificed at time 24 h. Data are presented as the mean ± SEM (). Differences among groups were analyzed by one-way ANOVA with Tukey’s post hoc test. Different from the sham group. Different from the saline (S) group at the same time point. Different from other time points in the same group ().