Mediators of Inflammation / 2017 / Article / Tab 2

Review Article

Skin Immune Landscape: Inside and Outside the Organism

Table 2

Major constituents of the adaptive immunity.

CompartmentsCellsInflammatory mediators

DermisDCsMHC, CD80/CD86, IFN-β
CTLEnzymes, caspases
TH1IFN-γ, IL-2, TNF-α, IL-12
TH2IL-4, IL-5, IL-13 IL-4, IL-6, IL-15
TH17IL-17, IL-22
TH 22IL-22
B cellsIgA, IgE, IgG, IgD, IgM

DCs: dendritic cells; CTL: cytotoxic T lymphocytes; TH: T helper; MHC: major histocompatibility class; IFN: interferon; CD: cluster of differentiation; IL: interleukin; TNF: tumor necrosis factor; Ig: immunoglobulin.