Gene Electrotransfer of Plasmid-Encoding IL-12 Recruits the M1 Macrophages and Antigen-Presenting Cells Inducing the Eradication of Aggressive B16F10 Murine Melanoma

<div>(a) Tumor growth of B16F10 tumors in C57/Bl6 after IL-12 GET compared to that in the control animal groups. The experiments were performed independently twice. (b) ELISA assay for the detection of mIL-12 in the LPS group (positive control) on days 1, 4, and 8 and in the pORF-mIL-12-ORT + EP group on days 1, 4, 8, and 14. (c) Detection of mIFN<i>γ</i> in the LPS and pORF-mIL-12-ORT + EP groups on days 1, 4, 8, and 14 using an ELISA assay.</div>

Mediators of Inflammation

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Figure 2: Gene Electrotransfer of Plasmid-Encoding IL-12 Recruits the M1 Macrophages and Antigen-Presenting Cells Inducing the Eradication of Aggressive B16F10 Murine Melanoma 

Figure 2 | Gene Electrotransfer of Plasmid-Encoding IL-12 Recruits the M1 Macrophages and Antigen-Presenting Cells Inducing the Eradication of Aggressive B16F10 Murine Melanoma 