Review Article

Paracoccidioides Spp.: Virulence Factors and Immune-Evasion Strategies

Table 3

Biochemical study of P. brasiliensis and P. lutzii cell wall composition in the presence of horse serum. Yeast cells were grown on YPD or YPD supplemented with 5% horse serum for 4 days at 37°C. HS, horse serum.

Cell wall polysaccharides contentP. brasiliensis strain Pb73, yeast phase
Grown on
P. lutzii strain Pb01, yeast phase
Grown on
YPDYPD+ 5%HSYPDYPD + 5%HS

Chitin15.7 ± 0.312.8 ± 0.321.1 ± 0.721.4 ± 1.0
α-(1,3)-Glucan17.9 ± 0.232.5 ± 1.125.7 ± 0.425.2 ± 0.3
β-(1,3)-Glucan5.8 ± 0.35.1 ± 0.13.8 ± 0.32.3 ± 0.3