Research Article

Innate Immunity of Adipose Tissue in Rodent Models of Local and Systemic Staphylococcus aureus Infection

Table 3

Effect of lipopeptide stimulation on the secretion of adipokines, chemokines, and cytokines into the supernatant of mature 3T3-L1 adipocytes and of undifferentiated fibroblasts.
(a) 3T3-L1 adipocytes

Ctrl.50 ng/ml Pam3Cys100 ng/ml Pam3Cys

MCP-1 [ng/ml]
Adiponectin [µg/ml]
Lipocalin-2 [µg/ml]
Resistin [µg/ml]

Ctrl.50 ng/ml MALP-2100 ng/ml MALP-2

MCP-1 [ng/ml]
Adiponectin [µg/ml]
Lipocalin-2 [µg/ml]
Resistin [µg/ml]

(b) 3T3-L1 fibroblasts

Ctrl.50 ng/ml Pam3Cys100 ng/ml Pam3Cys

MCP-1 [ng/ml]
IL-6 [pg/ml]

Ctrl.50 ng/ml MALP-2100 ng/ml MALP-2

MCP-1 [ng/ml]
IL-6 [pg/ml]

Mean concentrations ± double standard error of the mean (2x SEM) are summarized by using 4–6 wells each. Concentrations were normalized to total cell protein. MCP-1, monocyte chemoattractant protein-1; and .