Innate Immunity of Adipose Tissue in Rodent Models of Local and Systemic Staphylococcus aureus Infection
Table 3
Effect of lipopeptide stimulation on the secretion of adipokines, chemokines, and cytokines into the supernatant of mature 3T3-L1 adipocytes and of undifferentiated fibroblasts.
(a) 3T3-L1 adipocytes
Ctrl.
50 ng/ml Pam3Cys
100 ng/ml Pam3Cys
MCP-1 [ng/ml]
Adiponectin [µg/ml]
Lipocalin-2 [µg/ml]
Resistin [µg/ml]
Ctrl.
50 ng/ml MALP-2
100 ng/ml MALP-2
MCP-1 [ng/ml]
Adiponectin [µg/ml]
Lipocalin-2 [µg/ml]
Resistin [µg/ml]
(b) 3T3-L1 fibroblasts
Ctrl.
50 ng/ml Pam3Cys
100 ng/ml Pam3Cys
MCP-1 [ng/ml]
IL-6 [pg/ml]
Ctrl.
50 ng/ml MALP-2
100 ng/ml MALP-2
MCP-1 [ng/ml]
IL-6 [pg/ml]
Mean concentrations ± double standard error of the mean (2x SEM) are summarized by using 4–6 wells each. Concentrations were normalized to total cell protein. MCP-1, monocyte chemoattractant protein-1; and .