Table 2: Serum levels of adipokines and TRAIL according to abdominal obesity categories.

Parameters

Waist circumference (cm)

≤79.9 []

80–87.9 []

≥88 []

IL-8 (pg/mL)

2.7 ± 0.9

3.3 ± 0.9

3.4 ± 1.9

NS

TNF-α (pg/mL)

1.7 (1.3–2.4)

1.9 (1.2–2.6)

2.0 (1.4–2.7)

NS

IL-6 (pg/mL)

0.4 (0.3–0.8)

0.5 (0.3–0.7)

1.0 (0.4–1.7)^{a,b}

<0.01

MCP-1 (pg/mL)

207 (147–306)

193 (158–276)

213 (166–278)

NS

Resistin (pg/mL)

11,051 ± 4628

13,398 ± 7721^{a}

13,540 ± 5476^{a}

<0.05

Adiponectin (μg/mL)

80 (49–170)

69 (37–158)^{a}

43 (22–57)^{a,b}

<0.01

HGF (pg/mL)

215 (108–318)

306 (187–483)

377 (272–571)^{a,b}

<0.01

NGF (pg/mL)

0.9 (0.7–1.2)

1.1 (0.9–1.5)

1.2 (0.8–1.6)

NS

Adipsin (μg/mL)

3.7 (3.1–4.5)

3.9 (3.3–4.8)

4.6 (4.8–6.0)^{a,b}

<0.01

Leptin (ng/mL)

6 (4–13)

14 (6–22)^{a}

29 (13–39)^{a,b}

<0.01

Lipocalin-2/ngal (ng/mL)

135 ± 48

157 ± 82

160 ± 60^{a}

<0.05

PAI-1 total (ng/mL)

46 ± 22

53 ± 22

61 ± 22^{a}

<0.01

TRAIL

100 ± 20

110 ± 23^{a}

110 ± 25

NS

Data presented are expressed as mean ± standard deviation for normal continuous variables; median (interquartile range) for nonnormal continuous variables. ANOVA (post hoc test: Tukey) or Kruskall-Wallis (post hoc test: Wilcoxon–Mann–Whitney test followed by Bonferroni correction). versus normal; versus overweight. IL: interleukin; PAI-1 total: plasminogen activator inhibitor-1; TNF-α: tumor necrosis factor alpha; MCP-1: monocyte chemoattractant protein; HGF: hepatocyte growth factor; ngal: neutrophil gelatinase-associated lipocalin; NGF: nerve growth factor.