Key Role of STAT4 Deficiency in the Hematopoietic Compartment in Insulin Resistance and Adipose Tissue Inflammation

Table 2

Body weight, plasma lipids, and glucose.

	Rag control	CD4+; STAT4−/−	CD4+; STAT4+/+	CD8+; STAT4−/−	CD8+; STAT4+/+
Body weight (g)	39.3 ± 2.0	44.9 ± 3.0	38.1 ± 6.3	45.4 ± 2.9	38.9 ± 5.6
Triglycerides (mg/dL)	46.1 ± 8.5	65.2 ± 13.5	111.6 ± 54.5	40.7 ± 9.5	119.8 ± 79.2
Free FA (mEq/L)	1.3 ± 0.17	0.89 ± 0.25	1.15 ± 0.25	0.68 ± 0.18 ^#	1.17 ± 0.17
Cholesterol (mg/dL)	170.9 ± 16.2	162.1 ± 16.4	231.9 ± 77.8	246.5 ± 60.5	215.2 ± 30.9
Fasting glucose (mg/dL)	265.9 ± 21.8	262.7 ± 65.8	259.6 ± 51.8	280.5 ± 92.3	265.1 ± 46.8

Results represent fasting body weights and plasma values at time of sacrifice. Data is from = 6–12 mice/group and represents mean ± SD. Statistical analysis was performed using one-way ANOVA and the null hypothesis was rejected for . Significant compared to Rag controls (). Significant compared to CD8+STAT4+/+ mice ().