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Figure 3: Curcumin prevented PMMA particle-induced osteoclastogenesis. Histomorphometric analysis of (a) the ratio of remaining area of bone (%), (b) the eroded surface area (mm2), (c) the number of TRAP-positive multinucleated osteoclasts, and (d) the percentage of osteoclast surface per bone surface (OcS/BS, %) within the ROI in each group (/group; versus the PBS group; versus the PBS group; # versus the PMMA group).