Different Dietary Proportions of Fish Oil Regulate Inflammatory Factors but Do Not Change Intestinal Tight Junction ZO-1 Expression in Ethanol-Fed Rats
Table 3
Hepatic histopathology scores in each group1,2.
—
F25
F57
Ethanol and fish oil
Fatty change (macrovesicular)
C
1.6 ± 0.2
1.2 ± 0.2
1.2 ± 0.2
0.1779
E
2.8 ± 0.2e
1.8 ± 0.2f
1.6 ± 0.2f
Fatty change (microvesicular)
C
0.0 ± 0.0
0.0 ± 0.0
0.0 ± 0.0
<0.0001
E
1.8 ± 0.2e
0.0 ± 0.0f
0.0 ± 0.0f
Inflammatory cell infiltration
C
1.6 ± 0.2a
1.8 ± 0.2a
0.6 ± 0.2b
0.0635
E
2.8 ± 0.2e
1.8 ± 0.2f
1.6 ± 0.4f
Cell degeneration and necrosis
C
1.4 ± 0.2a
1.0 ± 0.0ab
0.8 ± 0.2b
0.4831
E
3.0 ± 0.0e
2.4 ± 0.2f
2.0 ± 0.0f
Bile duct hyperplasia
C
1.4 ± 0.2
1.4 ± 0.2
1.0 ± 0.3
0.1288
E
1.0 ± 0.0
1.4 ± 0.2
1.6 ± 0.2
Fibrosis
C
0.8 ± 0.4
1.4 ± 0.2
0.8 ± 0.2
0.7725
E
1.0 ± 0.3
1.4 ± 0.2
0.6 ± 0.2
1Values are expressed as the mean ± SEM. Means between groups C and E with significantly differ (). Means among groups C, CF25, and CF57 with different superscript letters (a, b) significantly differ (). Means among groups E, EF25, and EF57 with different superscript letters (e, f) significantly differ (). 2Details are the same as those described in the footnotes of Table 1.