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Mediators of Inflammation
Volume 2017, Article ID 5858315, 13 pages
https://doi.org/10.1155/2017/5858315
Research Article

A Novel Role for Brain Natriuretic Peptide: Inhibition of IL-1 Secretion via Downregulation of NF-kB/Erk 1/2 and NALP3/ASC/Caspase-1 Activation in Human THP-1 Monocyte

Department of Experimental Medicine, University of Perugia, Piazzale L. Severi 1, 06129 Perugia, Italy

Correspondence should be addressed to Letizia Mezzasoma; ti.gpinu@amosazzem.aizitel

Received 8 September 2016; Revised 15 December 2016; Accepted 18 January 2017; Published 26 February 2017

Academic Editor: Hermann Gram

Copyright © 2017 Letizia Mezzasoma et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [4 citations]

The following is the list of published articles that have cited the current article.

  • Letizia Mezzasoma, Matthew Peirce, Alba Minelli, and Ilaria Bellezza, “Natriuretic Peptides: The Case of Prostate Cancer,” Molecules, vol. 22, no. 10, pp. 1680, 2017. View at Publisher · View at Google Scholar
  • Liugen Gu, Zhenming Ge, Yamin Wang, Meiqin Shen, Ping Zhao, and Weichang Chen, “Double-stranded RNA-dependent kinase PKR activates NF-κB pathway in acute pancreatitis,” Biochemical and Biophysical Research Communications, 2018. View at Publisher · View at Google Scholar
  • Amanda D'Espessailles, Yuly A. Mora, Cecilia Fuentes, and Mariana Cifuentes, “Calcium-sensing receptor activates the NLRP3 inflammasome in LS14 preadipocytes mediated by ERK1/2 signaling,” Journal of Cellular Physiology, 2018. View at Publisher · View at Google Scholar
  • Ye-Li Zhao, Zhuo-Yu Lu, Xuan Zhang, Wei-Wei Liu, Guo-Dong Yao, Xiao-Ling Liu, Wei Liu, Qing-Jie Wu, Toshihiko Hayashi, Masayuki Yamato, Hitomi Fujisaki, Shunji Hattori, Yuji Atsuzawa, Shin-ichi Tashiro, Satoshi Onodera, and Takashi Ikejima, “Gelatin promotes cell aggregation and pro-inflammatory cytokine production in PMA-stimulated U937 cells by augmenting endocytosis-autophagy pathway,” The International Journal of Biochemistry & Cell Biology, 2018. View at Publisher · View at Google Scholar