MBD2 Regulates Th17 Cell Differentiation and Experimental Severe Asthma by Affecting IRF4 Expression

Figure 5

Expression of IRF4 in three groups. (a) Lung tissues were stained for immunohistochemistry (anti-IRF4) of the three groups. Histological analyses of lungs from the severe and conventional groups exhibited markedly enhanced cells with stained IRF4 compared with those of the saline group. (b) Western blot analyses detected IRF4 protein expression in the lungs of the three groups. The IRF4 protein expression from the severe and conventional groups were higher than that from the saline group. (c) Western blot analyses detected IRF4 protein expression in the splenocytes of the three groups. The IRF4 protein expression from the severe and conventional groups were higher than that from the saline group.

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