Curcumin Alters Neural Plasticity and Viability of Intact Hippocampal Circuits and Attenuates Behavioral Despair and COX-2 Expression in Chronically Stressed Rats

Figure 2

Effect of curcumin on the protein expression of brain-derived neurotrophic factor (BDNF) and cyclooxygenase-2 (COX-2) in rats with chronic stress-induced hippocampal impairment (/group). (a) The protein level of BDNF in rat hippocampus was measured by Western blot analysis using anti-BDNF specific antibody. (b) The protein level of COX-2 in rat hippocampus was measured by Western blot analysis using anti-COX-2 specific antibody. The data were normalized against β-actin levels and expressed as percentage of control values. versus sham group. versus control group.

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