5-HT Drives Mortality in Sepsis Induced by Cecal Ligation and Puncture in Mice

Figure 14

Lack of 5-HT decreases the level of ROS in CLP-induced sepsis. DHE fluorescence intensity was used to detect ROS after CLP in the lung and liver. The KO-CLP sepsis group had a lower level of fluorescence intensity than the WT-CLP sepsis group in both the liver and lung. All data are expressed as the mean ± SD. versus the WT-CLP group.