5-HT Drives Mortality in Sepsis Induced by Cecal Ligation and Puncture in Mice

Figure 2

Lack of 5-HT reduces the clinical score and retains low body temperature in CLP-induced sepsis in mice. The clinical score was assessed at 24 h, and the temperatures of the mice were measured at 6 h and 24 h after CLP-induced sepsis (, mean ± SD, clinical score, versus the WT-CLP group; temperature, versus the WT-CLP group 24 h after CLP-induced sepsis).