Intranasal Delivery of miR-146a Mimics Delayed Seizure Onset in the Lithium-Pilocarpine Mouse Model

Figure 3

Relative levels of miR-146a and its target mRNAs 2 h after pilocarpine administration by real-time qPCR. (a) In comparison with the APE group, the relative level of miR-146a increased 3.42 times in the hippocampus of the APT group. ((b) and (c)) The expression of its target mRNAs IRAK-1 and TRAF-6 reduced 0.46 and 0.36 times in the hippocampus of the APT group compared with the APE group, respectively. Values are presented as the means ± SD ().

(a)

(b)

(c)