Intranasal Delivery of miR-146a Mimics Delayed Seizure Onset in the Lithium-Pilocarpine Mouse Model

Figure 4

Expression of typical inflammatory modulators 2 h after pilocarpine administration. (a) The relative NF-κB level reduced 0.68 times in the hippocampus of the APT group compared to the APE group according to real-time qPCR and confirmed by WB; ((b)–(d)) the expression of TNF-α, IL-1β, and IL-6 reduced 0.22, 0.17, and 0.23 times in the hippocampus of the APT group compared to the APE group, respectively. Values are presented as the means ± SD (; ).

(a)

(b)

(c)

(d)