Multiple Immunosuppressive Effects of CpG-c41 on Intracellular TLR-Mediated Inflammation

Figure 2

CpG-c41 alters TLR activation-induced cytokine secretion in vivo. WT mice received intraperitoneal injection of polyI:C (40 μg/20 g), R848 (10 μg/20 g), or CpG-1826 (160 μg/20 g), as indicated. They also received CpG-c41 (320 μg/20 g) or normal saline (NS) by tail vein injection. Cytokines in sera from the indicated time points were determined by ELISA. . Bars represent mean ± SEM ().

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