Figure 5: Changes in the proportions of the major effector T-helper cell subsets in RA patients in whom long-term follow-up data from the initiation of anti-TNF therapy were available (). 7 patients from the initial short-term cohort (7) proved to be long-term responders, whereas the other 6 patients lost the initial response and therefore belonged to the nonresponder group. Measurement time points: baseline: at anti-TNF initiation, short term: 8 weeks of anti-TNF treatment (previously published data (7), long-term: current measurement results after long-standing anti-TNF treatment. Data are presented as median (horizontal line within boxes), 25 and 75 percentile (horizontal borders of the boxes), and minimum and maximum (whiskers). A versus baseline, B versus short term.