Associations of Functional MicroRNA Binding Site Polymorphisms in IL23/Th17 Inflammatory Pathway Genes with Gastric Cancer Risk

Table 3

Demographic characteristics in GC patients and controls.

Variables	Cases (%)	Controls (%)	Test statistics	^b	OR (95% CI)
	()	()
Age (mean ± SD), year	57.93 ± 11.88	57.27 ± 12.15		0.36^a
Gender
Female	124 (24.80)	124 (24.80)			1
Male	376 (75.20)	376 (75.20)		1.00	1.00 (0.75, 1.33)
Smoking status
Never	202 (40.40)	255 (51.00)			1
Ever	298 (59.60)	245 (49.00)		<0.01	1.53 (1.20, 1.97)
Drinking status
Never	310 (62.00)	325 (65.00)			1
Ever	190 (38.00)	175 (35.00)		0.32	1.14 (0.88, 1.47)
Family history of GC
No	381 (76.20)	444 (88.80)			1
Yes	119 (23.80)	56 (11.20)		<0.01	2.48 (1.75, 3.50)

GC: gastric cancer; OR: odds ratio; CI: confidence interval; SD: standard deviation. ^a value for Student’s t-test. ^b value for two-sided χ² test.