Research Article

Associations of Functional MicroRNA Binding Site Polymorphisms in IL23/Th17 Inflammatory Pathway Genes with Gastric Cancer Risk

Table 6

Haplotype analysis of rs1468488 and rs887796 polymorphism sites in IL17RA.

HaplotypeCases (%)Controls (%)χ2ORadj (95% CI)aa

Hap1 (Crs1468488Ars887796)69 (6.90)67 (6.70)0.041.04 (0.73, 1.47)0.84
Hap2 (Trs1468488Ars887796)806 (80.60)807 (80.70)0.021.02 (0.81, 1.27)0.90
Hap3 (Trs1468488Grs887796)117 (11.70)122 (12.20)0.100.96 (0.73, 1.26)0.76

OR: odds ratio; CI: confidence interval. aOR with 95% CI and value for logistic regression analysis adjusted for smoking, drinking, and family history of GC.