Ischemia/Reperfusion Injury following Acute Myocardial Infarction: A Critical Issue for Clinicians and Forensic Pathologists

Figure 3

Histomorphological pictures showing the phenotypic results of altered pathways in IRI. (a) Mild calpain 1 expression in the left ventricle cardiac tissue of a patient who died following early reperfused AMI (calpain 1, antibody anti-calpain 1, Santa Cruz, USA). (b) NOX2 expression in the left ventricle cardiac tissue of a patient who died following prompt fibrinolysis in acute STEMI. (c) Strong immunopositivity to anti-nitrotyrosine antibody (Abcam, Cambridge, UK). (d) Mild immunopositivity to anti-iNOS (inducible nitric oxide synthase) antibody (Santa Cruz, CA, USA) in the left ventricle sample of a patient who died following reperfusion therapy in STEMI.

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