Neuroinflammation and ALS: Transcriptomic Insights into Molecular Disease Mechanisms and Therapeutic Targets

Figure 2

SALS-related PPI networks. (a) Graphical representation of the PPI network from inflammatory DEGs in SALS1. Nodes having a high degree are the ones that form most interactions with other nodes and were displayed as a big circle and dark colors. The right panel shows the top 50 nodes in PPI network order by descending degree value. (b) Graphical representation of the PPI network from inflammatory DEGs in SALS2. Nodes having a high degree are the ones that form most interactions with other nodes and were displayed as a big circle and dark colors. The right panel shows the top 50 nodes in PPI network order by descending degree value.

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