Saquinavir Ameliorates Liver Warm Ischemia-Reperfusion-Induced Lung Injury via HMGB-1- and P38/JNK-Mediated TLR-4-Dependent Signaling Pathways

<div>SQV could improve the lung injury induced by liver warm I/R. H&amp;E staining and histological alterations of lung parenchyma were graded (a). Degrees of lung permeability and edema were reflected by EBA and W/D ratio (b). The total cell counts and protein concentration in BALF (c). Apoptotic assay (Tunel<sup>+</sup>) was performed in the lung tissues of mice with or without SQV treatment after liver I/R (d). 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Mediators of Inflammation

fig2

Figure 2

Figure 2: Saquinavir Ameliorates Liver Warm Ischemia-Reperfusion-Induced Lung Injury via HMGB-1- and P38/JNK-Mediated TLR-4-Dependent Signaling Pathways 

Figure 2 | Saquinavir Ameliorates Liver Warm Ischemia-Reperfusion-Induced Lung Injury via HMGB-1- and P38/JNK-Mediated TLR-4-Dependent Signaling Pathways 