Th1/Th17-Related Cytokines and Chemokines and Their Implications in the Pathogenesis of Pemphigus Vulgaris

Figure 4

Skin lesions in Pemphigus vulgaris are associated with higher levels of IL-6 and CXCL8. Levels of (a) IL-2, (b) IL-6, and (c) CXL8 (IL-8) in Pemphigus vulgaris (PV) patients with no skin lesions (⬤) and PV patients with skin lesions (■). (d) Correlation between the frequency of lesions and time of treatment and (e) correlation between the frequency of skin lesions and dosage of glucocorticoids used to treat PV patients. Error bars represent median ± SD. , Mann–Whitney test was used in (a–c). The Spearman correlation test was used to evaluate the strength of association between the variables (d and e).

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