All-Trans Retinoic Acid Modulates TLR4/NF-κB Signaling Pathway Targeting TNF-α and Nitric Oxide Synthase 2 Expression in Colonic Mucosa during Ulcerative Colitis and Colitis Associated Cancer

Figure 5

Percentage of mixed leukocytes in areas with high or low expression of iNOS and TNF-α. Mixed leukocytes (inflammatory cell infiltrate) were counted in 4 wells nonoverlapping in areas of iNOS/TNF-α overexpression and areas with low expression. High density of mixed leukocytes was observed in areas of iNOS and TNF-α overexpression as compared with areas of low iNOS/TNF-α expression in colonic mucosa of UC and CAC patients ().

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