Research Article

All-Trans Retinoic Acid Modulates TLR4/NF-κB Signaling Pathway Targeting TNF-α and Nitric Oxide Synthase 2 Expression in Colonic Mucosa during Ulcerative Colitis and Colitis Associated Cancer

Figure 9

The expression of NF-κB (P50) and ikkγ in colonic mucosa of UC and CAC patients detected by IF. NF-κB (score 3) and ikkγ (score 3) expression was upregulated in colonic mucosa of active UC and CAC patients compared with control (score 0) (UC: ulcerative colitis, ; CAC: colitis associated cancer, ; C: control, normal mucosa, ).