TSG-6 Downregulates IFN-Alpha and TNF-Alpha Expression by Suppressing IRF7 Phosphorylation in Human Plasmacytoid Dendritic Cells

Figure 4

CpG-A and R837 induced TSG-6 expression in GEN2.2 cells. (a and b) Real-time PCR analysis and (c) ELISA analysis of GEN2.2 cells treated with CpG-A (2 μM) or R837 (10 ng/mL) shows induction of TSG-6 at both transcription and protein level. Graphs show data of at least 3 independent experiments performed in duplicate. Error bars indicate SEM. Paired Student's -test, , , and .

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