Research Article

Illicium verum Extract and Trans-Anethole Attenuate Ovalbumin-Induced Airway Inflammation via Enhancement of Foxp3+ Regulatory T Cells and Inhibition of Th2 Cytokines in Mice

Figure 4

Effect of IVE and AET on mRNA expression of Foxp3, IL-5, IL-13, and CCR3 and immunofluorescence staining for Foxp3 in lung tissue of OVA-induced asthmatic mice. (a) CCR3, (b) IL-5, (c) IL-13, and (d) Foxp3 mRNA expression. (e) Immunofluorescent staining for Foxp3 (green) and DAPI (DNA) (gray) in lung tissue. Results are expressed as mean ± SEM ( mice per group). , , and indicate statistically significant differences between the asthma control group and drug-treated group.
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