Research Article
Thrombopoietin Receptor Agonist Mitigates Hematopoietic Radiation Syndrome and Improves Survival after Whole-Body Ionizing Irradiation Followed by Wound Trauma
Figure 9
CI delays wound healing, but Alxn4100TPO increased the delay. Wound areas were measured on days 1, 3, 7, 14, 21, and 28. = 19–22 per group. Data are presented as mean ± SEM. For panel (a): versus RI. For panel (b), versus W + Alxn4100TPO. For panel (c): versus RI + Vehicle. For panel (d): versus CI + Vehicle. Veh: vehicle; W: wound; RI: 9.5 Gy; CI: 9.5 Gy and skin wound.
(a) Vehicle mice |
(b) Alxn4100TPO mice |
(c) Wounded mice |
(d) CI mice |