Osteopontin Impacts West Nile virus Pathogenesis and Resistance by Regulating Inflammasome Components and Cell Death in the Central Nervous System at Early Time Points

Figure 5

Transcription of inflammasome-associated molecules in WNV-infected brains. Transcriptional levels of (a) caspase 1, (b) NLRP3, (c) Mefv, and (d) PYCARD were measured by qRT-PCR, relative to GAPDH, on day 0 and day 5 post WNV infection, in WT (white bars) and in OPN KO (gray bars) brains. Results represent the mean ± SEM of 6 animals per group. , lines indicate compared groups.

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