Pretreatment Liver Injury Predicts Poor Prognosis of DLBCL Patients

Table 2

Univariate analyses on PFS and OS in DLBCL patients ().

Variates	2-year PFS rate (%)	value for PFS	2-year OS rate (%)	value for OS
IPI score		<0.001		<0.001
Low	91.6		94.9
Low-intermediate	68.1		85.0
High-intermediate	61.7		72.1
High	40.7		50.7
Ann Arbor stage		<0.001		<0.001
I-II	90.9		93.9
III-IV	54.3		68.3
Number of extranodal sites		0.019		0.176
≤1	80.0		85.6
≥2	62.9		75.6
Performance status (ECOG)		<0.001		<0.001
≤1	77.8		86.3
≥2	54.2		60.0
LDH		<0.001		<0.001
Normal	87.7		94.4
>Normal	55.0		65.1
Liver enzyme		<0.001		<0.001
Normal	79.8		88.0
>Normal	59.5		65.2
IL-2R		<0.001		<0.001
Normal	90.9		95.1
>Normal	63.2		74.9
IL-6		<0.001		0.004
Normal	88.2		91.1
>Normal	69.2		80.1
IL-10		<0.001		<0.001
Normal	80.7		87.9
>Normal	64.0		74.5
TNF-α		0.003		0.005
Normal	88.0		96.5
>Normal	68.8		76.9
B symptoms		0.065		0.036
Present	78.0		85.8
Absent	63.9		72.1