The Role of Tissue Macrophage-Mediated Inflammation on NAFLD Pathogenesis and Its Clinical Implications

Figure 2

Schematic summary of macrophage polarization. Monocytes from peripheral blood differentiate in response to mediators in tissues, giving rise to different subsets: classically (M1) or alternatively (M2) activated macrophages that, respectively, lead to “bad” or “good” proinflammatory response.