Research Article
Urinary Levels of IL-1β and GDNF in Preterm Neonates as Potential Biomarkers of Motor Development: A Prospective Study
Table 2
Area under the curve (AUC) values for the measurement of inflammatory markers and neurotrophic factors in plasma and urine samples.
| Variables | Plasma | Urine | AUC values | 95% confidence interval | AUC values | 95% confidence interval |
| TNF | 0.534 | 0.327; 0.741 | 0.620 | 0.438; 0.802 | IL-12p70 | 0.378 | 0.195; 0.561 | 0.351 | 0.179; 0.523 | IL-1β | 0.561 | 0.373; 0.749 | 0.853 | 0.722; 0.984 | CXCL10/IP-10 | 0.443 | 0.246; 0.641 | 0.520 | 0.322; 0.718 | CCL2/MCP-1 | 0.353 | 0.168; 0.538 | 0.603 | 0.415; 0.791 | CXCL9/ MIG | 0.458 | 0.270; 0.645 | 0.559 | 0.364; 0.753 | CCL5/RANTES | 0.278 | 0.115; 0.442 | 0.568 | 0.388; 0.748 | CXCL8/IL-8 | 0.556 | 0.356; 0.755 | 0.567 | 0.384; 0.749 | BDNF | 0.668 | 0.498; 0.839 | 0.418 | 0.230; 0.607 | GDNF | 0.853 | 0.723; 0.983 | 0.392 | 0.195; 0.589 |
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