Mediators of Inflammation

Clinical Study

The Effect of Transcutaneous Electrical Acupoint Stimulation on Inflammatory Response in Patients Undergoing Limb Ischemia-Reperfusion

Table 4

Plasma CRP, CCL2, CXCL8, IL-1, IL-6, TNF-α, and IL-10 levels ( in each group). Data are expressed as mean ± standard deviation.


	Groups	T0	T5

CRP (pg/mL)	I/R	7.9 ± 1.2	8.4 ± 1.6
CRP (pg/mL)	TEAS	7.7 ± 2.0	8.0 ± 1.9
CCL2 (pg/mL)	I/R	108.8 ± 38.8	154.2 ± 42.9
CCL2 (pg/mL)	TEAS	107.1 ± 31.0	111.7 ± 50.0^#
CXCL8 (pg/mL)	I/R	8.1 ± 3.0	24.2 ± 6.2
CXCL8 (pg/mL)	TEAS	8.5 ± 3.4	16.3 ± 4.2^,#
IL-1 (pg/mL)	I/R	18.6 ± 4.4	31.4 ± 9.3
IL-1 (pg/mL)	TEAS	17.7 ± 4.3	23.9 ± 7.5^,#
IL-6 (pg/mL)	I/R	6.1 ± 2.0	61.6 ± 4.5
IL-6 (pg/mL)	TEAS	5.4 ± 1.0	30.4 ± 4.5^,#
TNF-α (pg/mL)	I/R	16.7 ± 6.0	20.8 ± 8.9
TNF-α (pg/mL)	TEAS	17.2 ± 7.7	12.0 ± 4.7^,#
IL-10 (pg/mL)	I/R	2.5 ± 1.0	2.8 ± 1.2
IL-10 (pg/mL)	TEAS	2.9 ± 1.2	3.6 ± 1.3

versus T0. ^# versus the I/R group. I/R: ischemia-reperfusion; CRP: C-reactive protein; CCL2: C-C motif chemokine ligand 2; CXCL8: C-X-C motif chemokine ligand 8; IL-1: interleukin-1; IL-6: interleukin-6; IL-10: interleukin-10; TEAS: transcutaneous electrical acupoint stimulation; TNF-α: tumor necrosis factor-α.