Persistent Unresolved Inflammation in the Mecp2-308 Female Mutated Mouse Model of Rett Syndrome

Table 2

Biological functions and APR role of the differentially expressed plasma proteins in the Mecp2-308 female mouse model.

Protein name	Short name	Biological functions (source: ExPASy)	APR proteins
Serotransferrin	TRFE	Iron binding and transport	(−)
Albumin	ALBU	Transport and regulation of colloidal osmotic pressure	(−)
Kininogen-1	KNG1	Mediator of inflammation and coagulation and protease inhibitor	(+)
Alpha-fetoprotein	FETA	Inflammation and fatty acid and metal binding	(+)
Mannose-binding protein C	MBL2	Innate immune defense and inflammation modulation	(+)
Apolipoprotein A1	APOA1	Lipid transport and metabolism	(−)
Alpha-1-antitrypsin	A1AT	Inflammation, coagulation, and protease inhibition	(+)
CD5 antigen-like	CD5L	Regulation of mechanisms in inflammatory responses	NA
Alpha-2-macroglobulin	A2M	Inflammation, coagulation, and protease inhibition	(+)
Vitamin D-binding protein	VTDB	Vitamin D sterol carrier	NA

APR: acute phase response; (+): positive APR proteins; (−): negative APR proteins; NA: not applicable.