Research Article

High Fat Diet Alters Gut Microbiota and the Expression of Paneth Cell-Antimicrobial Peptides Preceding Changes of Circulating Inflammatory Cytokines

Figure 3

Effect of HF consumption on the relative expression of Paneth cell-antimicrobial peptides. Except for cryptdin 5, the mRNA expressions of lysozyme, Reg IIIγ, and angiogenin 4 were significantly reduced at either 8 weeks or 12 and 16 weeks of HF feeding.