Table of Contents Author Guidelines Submit a Manuscript
Mediators of Inflammation
Volume 2017 (2017), Article ID 9524594, 8 pages
https://doi.org/10.1155/2017/9524594
Research Article

Middermal Elastolysis: Dermal Fibroblasts Cooperate with Inflammatory Cells to the Elastolytic Disorder

1Department of Molecular and Developmental Medicine, Section of General Pathology, University of Siena, Via Aldo Moro 6, 53100 Siena, Italy
2Department of Medicine, Surgery, and Neurosciences, Unit of Dermatology, University of Siena, Viale Bracci, 53100 Siena, Italy
3Unit of Pathological Anatomy, AOU Siena, Viale Bracci, 53100 Siena, Italy
4Department of Medicine, Surgery, and Neurosciences, Unit of Pathological Anatomy, University of Siena, Viale Bracci, 53100 Siena, Italy

Correspondence should be addressed to Eleonora Cavarra; ti.isinu@arravac.aronoele

Received 16 May 2017; Revised 25 July 2017; Accepted 5 September 2017; Published 17 September 2017

Academic Editor: Juarez A. S. Quaresma

Copyright © 2017 Giovanna De Cunto et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. W. B. Shelley and M. G. Wood, “Wrinkles due to idiopathic loss of mid-dermal elastic tissue,” British Journal of Dermatology, vol. 97, pp. 441–445, 1977. View at Publisher · View at Google Scholar · View at Scopus
  2. I. Patroi, G. Annessi, and G. Girolomoni, “Mid-dermal elastolysis: a clinical, histologic, and immunohistochemical study of 11 patients,” Journal of the American Academy of Dermatology, vol. 48, pp. 846–851, 2003. View at Publisher · View at Google Scholar · View at Scopus
  3. T. Gambichler, “Mid-dermal elastolysis revisited,” Archives of Dermatological Research, vol. 302, no. 2, pp. 85–93, 2010. View at Publisher · View at Google Scholar · View at Scopus
  4. M. Fimiani, C. Mazzatenta, C. Alessandrini, P. Marcolongo, P. Calzoni, and L. Andreassi, “Mid-dermal elastolysis: an ultrastructural and biochemical study,” Archives of Dermatological Research, vol. 287, no. 2, pp. 152–157, 1995. View at Google Scholar
  5. E. Cavarra, M. Fimiani, G. Lungarella et al., “UVA light stimulates the production of cathepsin G and elastase-like enzymes by dermal fibroblasts: a possible contribution to the remodeling of elastotic areas in sun-damaged skin,” Biological Chemistry, vol. 383, no. 1, pp. 199–206, 2002. View at Publisher · View at Google Scholar · View at Scopus
  6. T. Gambichler and M. Skrygan, “Decreased lysyl oxidase-like 2 expression in mid-dermal elastolysis,” Archives of Dermatological Research, vol. 305, no. 4, pp. 359–363, 2013. View at Publisher · View at Google Scholar · View at Scopus
  7. M. E. Martinez-Escala, E. Rozas, R. M. Pujol, and J. E. Herrero-Gonzalez, “Mid-dermal elastolysis: another dermatological clue to autoimmunity?” Acta Dermato-Venereologica, vol. 92, no. 4, pp. 434-435, 2012. View at Publisher · View at Google Scholar · View at Scopus
  8. G. Wagner and M. M. Sachse, “Elastolysis mediodermalis - case report and review of literature,” Journal der Deutschen Dermatologischen Gesellschaft, vol. 9, pp. 810–814, 2011. View at Publisher · View at Google Scholar · View at Scopus
  9. K. G. Lewis, L. Berkovitch, S. W. Dill, and L. Robinson-Bostom, “Acquired disorders of elastic tissue: part II. Decreased elastic tissue,” Journal of the American Academy of Dermatology, vol. 51, no. 2, pp. 165–185, 2004. View at Publisher · View at Google Scholar
  10. M. Sariahmetoglu, B. D. Crawford, H. Leon et al., “Regulation of matrix metalloproteinase-2 (MMP-2) activity by phosphorylation,” FASEB Journal, vol. 21, no. 10, pp. 2486–2495, 2007. View at Publisher · View at Google Scholar · View at Scopus
  11. B. Ortel, K. Rappersberger, and K. Konrad, “Middermal elastolysis in an elderly man with evidence of elastic fiber phagocytosis,” Archives of Dermatology, vol. 128, no. 1, pp. 88–90, 1992. View at Publisher · View at Google Scholar
  12. J. C. Sterling, N. Coleman, and R. J. Pye, “Mid-dermal elastolysis,” British Journal of Dermatology, vol. 130, no. 4, pp. 502–506, 1994. View at Publisher · View at Google Scholar · View at Scopus
  13. I. Neri, A. Patrizi, P. A. Fanti, B. Passarini, L. Badiali-De Giorgi, and C. Varotti, “Mid-dermal elastolysis: a pathological and ultrastructural study of five cases,” Journal of Cutaneous Pathology, vol. 23, no. 2, pp. 165–169, 1996. View at Publisher · View at Google Scholar · View at Scopus
  14. G. Lungarella, E. Cavarra, M. Lucattelli, and P. A. Martorana, “The dual role of neutrophil elastase in lung destruction and repair,” The International Journal of Biochemistry & Cell Biology, vol. 40, no. 6-7, pp. 1287–1296, 2008. View at Publisher · View at Google Scholar · View at Scopus
  15. R. P. Mechams, T. J. Broekelmann, C. J. Fliszar, and S. D. Shapiro, “Elastin degradation by matrix metalloproteinases,” The Journal of Biological Chemistry, vol. 272, no. 29, pp. 18071–18076, 1997. View at Publisher · View at Google Scholar · View at Scopus
  16. G. Lungarella, E. Cavarra, S. Fineschi, and M. Lucattelli, “Dual role for proteases in lung inflammation,” in Proteases and their Receptors in Inflammation, Progress in Inflammation Research, N. Vergnolle and M. Chignard, Eds., pp. 123–144, Springer, Basel AG, 2011. View at Publisher · View at Google Scholar
  17. J.-M. Sallenave and S. D. Shapiro, “Proteases and antiproteases in development, homeostasis and disease: the old, the new, and the unknown,” The International Journal of Biochemistry & Cell Biology, vol. 40, no. 6-7, pp. 1066-1067, 2008. View at Publisher · View at Google Scholar · View at Scopus
  18. S. Löffek, O. Schilling, and C.-W. Franzke, “Biological role of matrix metalloproteinases: a critical balance,” European Respiratory Journal, vol. 38, no. 1, pp. 191–208, 2011. View at Publisher · View at Google Scholar · View at Scopus
  19. A. M. Manicone and J. K. McGuire, “Matrix metalloproteinases as modulators of inflammation,” Seminars in Cell & Developmental Biology, vol. 19, no. 1, pp. 34–41, 2008. View at Publisher · View at Google Scholar · View at Scopus
  20. H.-J. Ra and W. C. Parks, “Control of matrix metalloproteinase catalytic activity,” Matrix Biology, vol. 26, pp. 587–596, 2007. View at Publisher · View at Google Scholar · View at Scopus