Increased Levels of sRAGE in Diabetic CKD-G5D Patients: A Potential Protective Mechanism against AGE-Related Upregulation of Fibroblast Growth Factor 23 and Inflammation

Table 1

Demographic, anthropometric, and clinical characteristics of CKD patients included in the study.

	All CKD ()	Non-DM CKD ()	DM CKD ()
Age (years)	62.41 (52.02–72.05)	61.21 ± 13.94	65.42 (54.83–70.94)	0.80
Male gender (, %)	55, 72.37%	35, 67.31%	20, 83.33%	0.18
BMI	27.20 ± 5.56	27.38 ± 5.28	24.14 (22.10–31.35)	0.50
HD (, %)	32, 42.11%	20, 38.46%	12, 50%	0.45
Smoking (, %)	9, 11.84%	4, 7.69%	5, 20.83%	0.13
Ex-smoking (, %)	29, 38.16%	20, 38.46%	9, 37.50%	1.00
Alcohol consumption (, %)	2, 2.63%	2, 3.85%	0, 0%	1.00
Hypertension (, %)	48, 63.16%	35, 67.30%	13, 54.17%	0.31
Cardiovascular diseases (, %)	22, 28.95%	12, 23.08%	10, 41.67%	0.11
Cerebrovascular diseases (, %)	4, 5.26%	2, 3.85%	2, 8.33%	0.59
Therapy with activated vitamin D	45, 59.21%	31, 59.62%	14, 58.33%	1.00
Therapy with paricalcitol	22, 28.95%	17, 32.69%	5, 20.83%	0.05

Data are expressed as median (25th–75th percentiles) or number and proportions. BMI: body mass index; HD: hemodialysis. Comparison between groups was performed by Mann–Whitney U test or Fisher exact test.