New Insights into Behçet’s Syndrome Metabolic Reprogramming: Citrate Pathway Dysregulation

Figure 2

Expression levels of ACLY mRNAs in study population. ACLY mRNA levels have been quantified in PBMCs from 21 healthy adult volunteers (control) and 39 BS patients (21 with inactive disease and 18 with active disease). Results are shown as box plots, where the horizontal line within the boxes represents the median, the boxes represent the first and third quartiles, and the bars outside the boxes represent the minimum and maximum values. Where indicated, the dashed bars represent the upper ends of the farthest observed data point within 1.5 times the interquartile range and the plus signs represent outliers. Dots within the boxes indicate the mean values. Differences among the groups were highly significant (, Kruskal-Wallis test). Pairwise comparisons were made with the post hoc Dunn’s test; results are shown with letters. Values sharing the same letter are not significantly different.