Mediators of Inflammation / 2018 / Article / Tab 1

Research Article

Raet1e Polymorphisms Are Associated with Increased Risk of Developing Premature Coronary Artery Disease and with Some Cardiometabolic Parameters: The GEA Mexican Study

Table 1

Biochemical, clinical, demographic, lifestyle, and tomography characteristics of the study population.

Control ()Premature CAD () value

Demographic
 Age (years)51 ± 954 ± 8<0.001
 Gender (% male)41.181.0<0.001
Biochemical and clinical characteristics
 Body mass index (kg/m2)27.9 [25.4-30.8]28.3 [25.9-31.1]0.004
 Systolic blood pressure (mmHg)112 [104-122]116 [106-127]<0.001
 Diastolic blood pressure (mmHg)71 [65-76]71 [66-78]0.011
 Total cholesterol (mg/dL)189 [166-210]160 [132-193]<0.001
 High density lipoprotein cholesterol (mg/dL)45 [36-55]37 [32-44]<0.001
 Low density lipoprotein cholesterol (mg/dL)115 [95-134]91 [69-116]<0.001
 Triglycerides (mg/dL)145 [107-201]162 [119-219]<0.001
 Aspartate aminotransaminase (IU/L)25 [21-30]26 [22-31]0.001
 Gamma-glutamyltransferase (IU/L)26 [18-42]33 [22-49]<0.001
 Adiponectin (μg/mL)8.1 [5.0-12.8]5.2 [3.2-8.1]<0.001
 Total (%)36.630.2<0.001
 Hypo-α-lipoproteinemia (%)52.067.2<0.001
 LDL pattern B (%)47.062.0<0.001
 Low adiponectin (%)42.857.5<0.001
 Hypertension (%)18.968.0<0.001
 Type 2 diabetes mellitus (%)9.835.6<0.001
 Increased aspartate aminotransaminase activity (%)36.338.90.207
 Increased gamma-glutamyltransferase activity (%)41.349.9<0.001
Tomography
 Total abdominal fat (cm2)432 [347-534]425 [339-523]0.254
 Visceral abdominal tissue (cm2)139 [104-180]168 [129-215]<0.001
 Subcutaneous abdominal fat (cm2)286 [218-366]245 [193-313]<0.001
Lifestyle
 Current smoking (%)22.811.7<0.001

Data are shown as deviation, median [interquartile range], or percentage. Student test, Mann-Whitney test or chi-square test. CAD = coronary artery disease; HDL = high-density lipoprotein; LDL = low-density lipoprotein.

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