Mediators of Inflammation / 2018 / Article / Tab 2

Research Article

Raet1e Polymorphisms Are Associated with Increased Risk of Developing Premature Coronary Artery Disease and with Some Cardiometabolic Parameters: The GEA Mexican Study

Table 2

Association of Raet1e gene polymorphisms with premature coronary artery disease.

Polymorphism (genotype frequency)MAFModelOR [95% CI]

rs6925151C > T
CCCTTT
Control ()392 (0.355)510 (0.462)202 (0.183)0.414Heterozygote1.250 [1.027-1.521]0.026
CAD ()373 (0.322)569 (0.491)216 (0.187)0.432Codominant 11.268 [1.018-1.581]0.034
rs9371533A > G
AAAGGG
Control ()293 (0.265)523 (0.474)288 (0.261)0.498Heterozygote1.255 [1.031-1.527]0.024
CAD ()314 (0.271)585 (0.505)259 (0.224)0.476
rs7756850G > C
GGGCCC
Control ()316 (0.285)523 (0.474)265 (0.240)0.477Heterozygote1.274 [1.047-1.550]0.016
CAD ()299 (0.258)584 (0.504)275 (0.237)0.490Codominant 11.294 [1.024-1.635]0.031
rs9383921C > T
CCCTTT
Control ()318 (0.288)525 (0.476)261 (0.236)0.474Heterozygote1.232 [1.012-1.499]0.037
CAD ()318 (0.261)584 (0.504)272 (0.235)0.487

Data are expressed as odds ratio (OR) and 95% confidence interval (CI) as assessed by multivariate logistic regression analysis. Each model was adjusted for age, gender, body mass index, current smoking, and type 2 diabetes mellitus. MAF = minor allele frequency.

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