Mediators of Inflammation / 2018 / Article / Tab 4

Research Article

Raet1e Polymorphisms Are Associated with Increased Risk of Developing Premature Coronary Artery Disease and with Some Cardiometabolic Parameters: The GEA Mexican Study

Table 4

Association of raet1e gene polymorphisms with clinical and metabolic parameters in the control group.

Polymorphism (genotype frequency)MAFModelOR [95% CI]

Controls
 Hipo-α-lipoproteinemia
  rs9371533AAAGGG
   No ()125 (0.236)277 (0.522)128 (0.242)0.503Heterozygote0.694 [0.545-0.885]0.003
   Yes ()168 (0.293)246 (0.429)160 (0.279)0.493Codominant 10.658 [0.490-0.884]0.005
 LDL pattern B
  rs566850CCCGGG
   No ()153 (0.262)277 (0.473)154 (0.265)0.502Additive0.815 [0.690-0.964]0.017
   Yes ()164 (0.316)245 (0.473)110 (0.211)0.448
  rs9383921CCCTTT
   No ()158 (0.270)273 (0.466)154 (0.263)0.496Recessive0.710 [0.533-0.946]0.019
   Yes ()161 (0.310)251 (0.484)107 (0.206)0.409
 AST > p75
  rs7756850CCCGGG
   No ()184 (0.261)343 (0.486)178 (0.253)0.496Dominant0.720 [0.549-0.944]0.018
   Yes ()133 (0.333)179 (0.446)88 (0.221)0.387
  rs9383921CCCTTT
   No ()183 (0.260)345 (0.489)177 (0.251)0.496Additive0.800 [0.673-0.951]0.011
   Yes ()136 (0.341)178 (0.446)85 (80.213)0.436Dominant0.695 [0.695-0.911]0.008
Codominant 20.651 [0.461-0.919]0.015

Data are expressed as odds ratio (OR) and 95% confidence interval (CI) as assessed by multivariate logistic regression analyses. All models were adjusted by age, gender, and body mass index. MAF = minor allele frequency; AST = aspartate aminotransaminase.

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